Causes and consequences of nuclear gene positioning
نویسندگان
چکیده
منابع مشابه
Causes and consequences of nuclear gene positioning.
The eukaryotic genome is organized in a manner that allows folding of the genetic material in the confined space of the cell nucleus, while at the same time enabling its physiological function. A major principle of spatial genome organization is the non-random position of genomic loci relative to other loci and to nuclear bodies. The mechanisms that determine the spatial position of a locus, an...
متن کاملCauses and Consequences of Male Infertility
Introduction: Infertility has various and innumerable causes, which pointing them out one by one is difficult and out of the scope of this paper. Infertility causes are different between males and females, and each case requires a separate and thorough research. The present study aimed to identify the male infertility causes. Methods: This study was conducted using a qualitative method, which ...
متن کاملtRNA Gene Identity Affects Nuclear Positioning
The three-dimensional organization of genomes is dynamic and plays a critical role in the regulation of cellular development and phenotypes. Here we use proximity-based ligation methods (i.e. chromosome conformation capture [3C] and circularized chromosome confrmation capture [4C]) to explore the spatial organization of tRNA genes and their locus-specific interactions with the ribosomal DNA. Di...
متن کاملSouth Asia and the Nuclear Future: Rethinking the Causes and Consequences of Nuclear Proliferation
• U.S. policy toward the nuclearization of India and Pakistan has shifted from sanctions and rollback to reluctant acceptance of their nuclear status. The United States now seeks to ensure that India and Pakistan become responsible nuclear powers and is emphasizing cooperative measures to prevent war, secure weapons and material from terrorist theft, and stop the further spread of nuclear weapons.
متن کاملNuclear Positioning
The nucleus is the largest organelle and is commonly depicted in the center of the cell. Yet during cell division, migration, and differentiation, it frequently moves to an asymmetric position aligned with cell function. We consider the toolbox of proteins that move and anchor the nucleus within the cell and how forces generated by the cytoskeleton are coupled to the nucleus to move it. The sig...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2017
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.199786